Atenolol or butoxamine injection at the lateral septum doesn't inhibit male sexual behavior in rats.
Indian J Physiol Pharmacol
;
2005 Jan; 49(1): 103-7
Article
in English
| IMSEAR
| ID: sea-107168
ABSTRACT
To investigate the role of specific adrenoreceptors subtypes on sexual behavior, atenolol, butoxamine, a mixture of atenolol and butoxamine, and saline (vehicle) were injected into the lateral septum in four different groups of sexually active male rats. Application of a mixture of atenolol and butoxamine produced inhibition of copulatory activity. On the other hand, application of either atenolol or butoxamine alone did not inhibit copulatory activity. But it produced stimulation of some of the components of male sexual behavior. Inability of either atenolol or butoxamine to inhibit the male sexual behavior, and inhibition of the same by the mixture of atenolol and butoxamine, indicate that both beta-adrenoreceptors at the lateral septum are involved in the elaboration of male sexual behavior. Stimulation of some components of sexual behavior on application of atenolol or butoxamine could be attributed to an unbalanced activity of beta-adrenoreceptors.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Atenolol
/
Septal Nuclei
/
Sexual Behavior, Animal
/
Female
/
Male
/
Butoxamine
/
Receptors, Adrenergic, beta
/
Rats, Wistar
/
Drug Combinations
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
2005
Type:
Article
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