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Anti-inflammatory property of ranitidine, a specific H2-receptor antagonist.
Indian J Physiol Pharmacol ; 1986 Jul-Sep; 30(3): 205-9
Article in English | IMSEAR | ID: sea-107436
ABSTRACT
The effects of ranitidine (2 mg/kg, po) and phenylbutazone (100 mg/kg po) have been studied in different models of acute and chronic inflammation in rats. Ranitidine showed significant anti-inflammatory activity in the four models used. This observation supports the concept that histamine has a pro-inflammatory role that is mediated via stimulation of H2-receptors.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Peritonitis / Arthritis / Arthritis, Experimental / Ranitidine / Rats / Rats, Inbred Strains / Turpentine / Female / Male / Carrageenan Language: English Journal: Indian J Physiol Pharmacol Year: 1986 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Peritonitis / Arthritis / Arthritis, Experimental / Ranitidine / Rats / Rats, Inbred Strains / Turpentine / Female / Male / Carrageenan Language: English Journal: Indian J Physiol Pharmacol Year: 1986 Type: Article