Hypoglycemic and antihyperglycemic effect of leaves of Vinca rosea linn.

Chattopadhyay, R R; Sarkar, S K; Ganguly, S; Banerjee, R N; Basu, T K

Chattopadhyay, R R; Sarkar, S K; Ganguly, S; Banerjee, R N; Basu, T K.

Indian J Physiol Pharmacol ; 1991 Jul; 35(3): 145-51

Article in English | IMSEAR | ID: sea-107647

ABSTRACT

ABSTRACT

Oral administration of water fraction of alcoholic extract of leaves of Vinca rosea (fam. apocynaeceae) led to marked lowering of blood glucose level in normal and streptozotocin induced diabetic rats. The hypoglycemic effect of the fraction was comparable with that of tolbutamide.

Subject(s)

Administration, Oral; Animals; Blood Glucose/drug effects; Diabetes Mellitus, Experimental/drug therapy; Drug Interactions; Female; Glucose/administration & dosage; Glucose Tolerance Test; Hypoglycemic Agents/pharmacology; Insulin/pharmacology; Male; Plant Extracts/pharmacology; Plants, Medicinal; Rats; Rats, Inbred Strains

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plants, Medicinal / Rats / Rats, Inbred Strains / Blood Glucose / Female / Male / Plant Extracts / Administration, Oral / Diabetes Mellitus, Experimental / Drug Interactions Language: English Journal: Indian J Physiol Pharmacol Year: 1991 Type: Article

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