Alloxan diabetes in Swiss mice: activity of Na(+)-K(+)-ATPase and succinic dehydrogenase.
Indian J Physiol Pharmacol
;
1995 Jul; 39(3): 271-4
Article
in English
| IMSEAR
| ID: sea-107670
ABSTRACT
The activities of two enzymes viz Na(+)-K(+)-ATPase and succinic dehydrogenase (SDH) in brain and liver of alloxan diabetic Swiss albino mice are reported. Alloxan diabetes caused significant decrease in the activity of Na(+)-K(+)-ATPase reflecting reduced glucose transport across the cell membrane. On the contrary, the observed enhanced activity of the enzyme SDH is attributed to increased supply of TCA cycle substrates from accelerated oxidation of fatty acids.
Full text:
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Index:
IMSEAR (South-East Asia)
Main subject:
Succinate Dehydrogenase
/
Blood Glucose
/
Brain
/
Female
/
Male
/
Sodium-Potassium-Exchanging ATPase
/
Diabetes Mellitus, Experimental
/
Liver
/
Liver Glycogen
/
Animals
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1995
Type:
Article
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