Evidence for melanin concentrating hormone (MCH) receptors mediating melanosome aggregation in Labeo melanophores.
Indian J Physiol Pharmacol
;
1990 Jul; 34(3): 187-90
Article
in English
| IMSEAR
| ID: sea-107816
ABSTRACT
Melanin concentrating hormone (MCH 5 x 10(-12)-5 x 10(-8) M) induced a concentration related, rapid and reversible pigment aggregation in innervated melanophores of Labeo rohita. In inducing melanosome aggregation MCH was found to be 10(4) times more potent than norepinephrine. Experiments employing phentolamine and propranolol suggest that MCH acts through its own specific receptors on the melanophores unrelated to adrenoceptors. MCH was able to aggregate the melanosomes even in the absence of extracellular Ca2+.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phentolamine
/
Pituitary Hormones
/
Propranolol
/
Skin
/
Carps
/
Norepinephrine
/
Cell Aggregation
/
Calcium
/
Receptors, Cell Surface
/
Hypothalamic Hormones
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1990
Type:
Article
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