Ocimum sanctum Linn--a study on gastric ulceration and gastric secretion in rats.

Mandal, S; Das, D N; De, K; Ray, K; Roy, G; Chaudhuri, S B; Sahana, C C; Chowdhuri, M K

Mandal, S; Das, D N; De, K; Ray, K; Roy, G; Chaudhuri, S B; Sahana, C C; Chowdhuri, M K.

Indian J Physiol Pharmacol ; 1993 Jan; 37(1): 91-2

Article in English | IMSEAR | ID: sea-107938

ABSTRACT

ABSTRACT

The antiulcerogenic property of Ocimum sanctum Linn (Tulsi) was studied in pyloric ligated and pyloric ligated & aspirin treated rats. The extract of OSL reduced the ulcer index, free & total acidity on acute and chronic administration. Seven days pretreatment with the drug increased the mucous secretion also. It may be concluded that OSL extract has antiulcerogenic property against experimental ulcers, and it is due to its ability to reduce acid secretion and increase mucous secretion.

Subject(s)

Animals; Anti-Ulcer Agents/pharmacology; Female; Gastric Juice/metabolism; Gastric Mucosa/drug effects; Hydrogen-Ion Concentration; India; Male; Plant Extracts/pharmacology; Plants, Medicinal; Rats; Rats, Wistar; Stomach Ulcer/drug therapy

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plants, Medicinal / Rats / Stomach Ulcer / Female / Male / Plant Extracts / Rats, Wistar / Gastric Juice / Gastric Mucosa / Hydrogen-Ion Concentration Country/Region as subject: Asia Language: English Journal: Indian J Physiol Pharmacol Year: 1993 Type: Article

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