A unified biochemical and continuum mechanical red blood cell membrane bilayer--couple model.
Indian J Physiol Pharmacol
;
2004 Oct; 48(4): 409-18
Article
in English
| IMSEAR
| ID: sea-108138
ABSTRACT
We study the shapes and biochemical characteristics of human red blood cells using a unified biochemical and continuum mechanical model. In particular, we model the crenated, echinocytic shapes and show how they may shift due to changes in the pH and various amphipaths affecting the osmotic pressure by also utilizing pressure as an independent variable. In contrast to earlier works which advocate that biochemical factors may be attributable to mechanical control parameters, cytoskeletal elastic constants and effective relaxed bilayer area difference of outer plasma membrane and inner protein-based membrane skeleton, our unified model agrees well with Band 3 diffusion experimental root mean square distance data.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Anion Exchange Protein 1, Erythrocyte
/
Diffusion
/
Erythrocyte Membrane
/
Lipid Bilayers
/
Mathematics
/
Models, Theoretical
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
2004
Type:
Article
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