Effect of adenosine and inosine on carbon tetrachloride-induced liver damage in rats.
Indian J Physiol Pharmacol
;
1992 Jan; 36(1): 39-42
Article
in English
| IMSEAR
| ID: sea-108223
ABSTRACT
Liver damage induced in rats by carbon tetrachloride (CCL4) was obvious macroscopically as well as microscopically in stained sections. Levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma glutamyl transpeptidase (gamma-GT) were also significantly raised. Adenosine and inosine effectively countered the damage when these were given before and during the period during which CCl4 produces the typical damage. The beneficial effect was seen in biochemical as well as pathological studies.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aspartate Aminotransferases
/
Rats
/
Rats, Inbred Strains
/
Male
/
Carbon Tetrachloride Poisoning
/
Adenosine
/
Alanine Transaminase
/
Gamma-Glutamyltransferase
/
Hemorrhage
/
Inosine
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1992
Type:
Article
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