Effect of carbachol injection in the medial preoptic area on sleep-wakefulness and body temperature in free moving rats.
Indian J Physiol Pharmacol
;
1994 Jul; 38(3): 163-8
Article
in English
| IMSEAR
| ID: sea-108280
ABSTRACT
The aim of the present study was to find out the changes in sleep-wakefulness and body temperature brought about by application of cholinergic agonist, carbachol, in the medial preoptic area (mPOA). Carbachol, when injected bilaterally into the mPOA of male rats, through chronically implanted cannulae, produced a fall in rectal temperature and long lasting arousal. There was temporal dissociation in the duration of changes produced in the two parameters. It is suggested that the cholinergic system at the medial preoptic area brings about arousal response and fall in body temperature through different circuits.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Preoptic Area
/
Rats
/
Sleep
/
Wakefulness
/
Body Temperature
/
Body Temperature Regulation
/
Male
/
Carbachol
/
Catheters, Indwelling
/
Analysis of Variance
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1994
Type:
Article
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