Influence of ascorbic acid on acid and alkaline phosphatase activities in some metabolically active tissues of aspirin treated rats.
Indian J Physiol Pharmacol
;
1997 Oct; 41(4): 421-3
Article
in English
| IMSEAR
| ID: sea-108289
ABSTRACT
ACP and ALP activities in plasma were increased in aspirin treated groups for a period of seven days. Ascorbic acid supplemented groups showed no significant change in plasma ACP activity, but a significant change in ALP activity was found. ACP and ALP activities in liver and kidney were decreased significantly in aspirin treated animals. ACP activities in liver and kidney in ascorbic acid supplemented groups showed no significant changes. No significant alteration of ALP activity in liver was found in ascorbic acid supplemented group but a significant changes was observed in kidney. Supplementation of ascorbic acid in high doses to rats fed aspirin can restore enzyme activities almost to the normal level.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ascorbic Acid
/
Rats
/
Acid Phosphatase
/
Male
/
Anti-Inflammatory Agents, Non-Steroidal
/
Aspirin
/
Rats, Wistar
/
Drug Interactions
/
Alkaline Phosphatase
/
Kidney
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1997
Type:
Article
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