Effect of ethosuximide on dopaminergically mediated behaviours.
Indian J Physiol Pharmacol
;
1981 Jul-Sep; 25(3): 274-8
Article
in English
| IMSEAR
| ID: sea-108364
ABSTRACT
Pretreatment with ethosuximide, a drug of choice for petit mal epilepsy, was found to inhibit the conditioned avoidance response in rats and the traction response in mice and to antagonise methamphetamine induced stereotyped behaviour in rats. Our results, which indicate the ethosuximide is capable of inhibiting the dopaminergically mediated behaviours, are in agreement with the recent reports stating that ethosuximide exerts central dopamine receptor blocking activity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Stereotyped Behavior
/
Avoidance Learning
/
Behavior, Animal
/
Humans
/
Male
/
Dopamine
/
Receptors, Dopamine
/
Ethosuximide
/
Haloperidol
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1981
Type:
Article
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