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Post-coital contraceptive efficacy of the seeds of Nigella sativa in rats.
Indian J Physiol Pharmacol ; 1995 Jan; 39(1): 59-62
Article in English | IMSEAR | ID: sea-108578
ABSTRACT
Hexane extract of the seeds of Nigella sativa L. prevented pregnancy in Sprague-Dawley rats treated orally at 2 g/kg daily dose on days 1-10 post-coitum. Significant antifertility activity was also observed in its column fractions and subfractions. At contraceptive dose, the active hexane extract exhibited only mild uterotrophic activity comparable almost to 0.002 mg/kg dose of 17 varies; is directly proportional to-Ethinylestradiol, but was devoid of any estrogenicity in the immature rat bioassay.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plants, Medicinal / Rats / Seeds / Vaginal Smears / Female / Pregnancy / Plant Extracts / Ovariectomy / Rats, Sprague-Dawley / Contraceptives, Postcoital Language: English Journal: Indian J Physiol Pharmacol Year: 1995 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plants, Medicinal / Rats / Seeds / Vaginal Smears / Female / Pregnancy / Plant Extracts / Ovariectomy / Rats, Sprague-Dawley / Contraceptives, Postcoital Language: English Journal: Indian J Physiol Pharmacol Year: 1995 Type: Article