Post-coital contraceptive efficacy of the seeds of Nigella sativa in rats.
Indian J Physiol Pharmacol
;
1995 Jan; 39(1): 59-62
Article
in English
| IMSEAR
| ID: sea-108578
ABSTRACT
Hexane extract of the seeds of Nigella sativa L. prevented pregnancy in Sprague-Dawley rats treated orally at 2 g/kg daily dose on days 1-10 post-coitum. Significant antifertility activity was also observed in its column fractions and subfractions. At contraceptive dose, the active hexane extract exhibited only mild uterotrophic activity comparable almost to 0.002 mg/kg dose of 17 varies; is directly proportional to-Ethinylestradiol, but was devoid of any estrogenicity in the immature rat bioassay.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plants, Medicinal
/
Rats
/
Seeds
/
Vaginal Smears
/
Female
/
Pregnancy
/
Plant Extracts
/
Ovariectomy
/
Rats, Sprague-Dawley
/
Contraceptives, Postcoital
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1995
Type:
Article
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