Calcium-transporters in myocardial cells.
Indian J Physiol Pharmacol
;
2006 Apr-Jun; 50(2): 99-113
Article
in English
| IMSEAR
| ID: sea-108723
ABSTRACT
This is a concise review of important calcium-transporters on the sarcolemma and organellar membranes of myocardial cells, and their functional roles in cell physiology. It briefly addresses L and T type calcium channels, store-operated calcium channel (SOC), sodium-calcium exchanger (NCX), and the plasma membrane calcium ATPase (PMCA) on the sarcolemma, ryanodine receptor (RyR), IP3 receptor (IP3R) and the sarcoplasmic reticulum (SR) calcium ATPase (SAERCA) on the SR membrane and their contributions to contraction and rhythm-generation. Several agonists and blockers for every transporter that are commonly used in research, and those with therapeutic applications have also been discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sarcolemma
/
Humans
/
Calcium Channels
/
Calcium-Transporting ATPases
/
Receptors, Cytoplasmic and Nuclear
/
Ryanodine Receptor Calcium Release Channel
/
Sodium-Calcium Exchanger
/
Calcium Channels, L-Type
/
Calcium Channels, T-Type
/
Cation Transport Proteins
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
2006
Type:
Article
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