Biochemical and pathological changes in response to hyperoxia and protection by antioxidants in rats.
Indian J Physiol Pharmacol
;
1992 Apr; 36(2): 97-100
Article
in English
| IMSEAR
| ID: sea-108833
ABSTRACT
A significant decrease in blood haemoglobin, reduced glutathione and protein in lung and liver, without any change in blood reduced glutathione, was observed in rats exposed to 80% oxygen. Hydrogen peroxide induced erythrocyte haemolysis was significantly increased following exposure to hyperoxia. The lungs of rats exposed to hyperoxia showed perivascular edema. Simultaneous treatment with antioxidants, vitamin A, C, or E, protected the animals against oxygen toxicity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Oxygen
/
Ascorbic Acid
/
Rats
/
Rats, Inbred Strains
/
Vitamin A
/
Vitamin E
/
Male
/
Hemoglobins
/
Proteins
/
Glutathione
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1992
Type:
Article
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