Hypothermia dn alphamethyldopa treatment.
Indian J Physiol Pharmacol
;
1976 Oct-Dec; 20(4): 216-20
Article
in English
| IMSEAR
| ID: sea-108987
ABSTRACT
The hypotensive drug alphamethyldopa, an inhibitor of serotonin synthesis, caused significant hypothermia ranging from 33.4 to 34.8 degrees C (t=3.09 at P less than 0.05) in four out of nine hypertensive patients, with evidence of cerebral atherosclerosis. The anti-serotonin effect of alphamethyldopa correlated with statistically significant (t=6.8 at P less than 0.001) fall in the 24 hour urinary 5-hydroxyindoleacetic acid on the third day of the therapy. The possible mode of hypothermic side effect is discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aged
/
Humans
/
Male
/
Intracranial Arteriosclerosis
/
Adolescent
/
Adult
/
Hydroxyindoleacetic Acid
/
Hypertension
/
Hypothermia
/
Methyldopa
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1976
Type:
Article
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