Perinatal mortality in eclampsia in relation to drug therapy.
Indian J Public Health
;
1994 Jan-Mar; 38(1): 3-7
Article
in English
| IMSEAR
| ID: sea-109352
ABSTRACT
Fifty-nine babies were born to eclamptic mothers among 7500 deliveries giving incidence of occurrence of 0.77 percent. The perinatal mortality in eclamptic babies was 32.7%, whereas the total perinatal mortality rate amongst all the deliveries was 10.5%. The mothers were treated within Group I--diazepam, Group II i chlorpromazine (largactil), phenargan and diazepam and Group III--largactil, phethidine and phenargan. The mortality rate was 23.8%, 18.8% and 66.6% respectively. The highest number of still-born i.e. six out of 8 occurred in Group III. Hundred percent still-born was noted in 28-32 weeks of gestation and birth weight less than 1.5 kg irrespective of drug regimes. Iargactil potentiates the respiratory depressant effect of pethidine and may cause high rate of still-birth and death after birth.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Promethazine
/
Birth Weight
/
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
/
Chlorpromazine
/
Infant Mortality
/
Gestational Age
/
Adult
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Public Health
Year:
1994
Type:
Article
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