Impact of improved treatment success on the prevalence of TB in a rural community based on active surveillance.
Article
in English
| IMSEAR
| ID: sea-110533
ABSTRACT
OBJECTIVE:
To study the impact of improved treatment outcome of a cohort of patients treated under DOTS strategy on the prevalence of pulmonary tuberculosis (TB) in the community.DESIGN:
The data from TB register of one Tuberculosis Unit (TU) in Tiruvallur district of Tamilnadu, and two TB disease surveys conducted in the same area during 1999-2003 were analysed. The successful treatment outcome was compared to the prevalence of TB in the subsequent cohort.RESULTS:
The proportion of patients who completed treatment successfully was 75.3% in the first cohort period. This higher proportion of treatment success among patients treated under DOTS in the first cohort period (1999-2001) compared to the 51-55% reported during SCC, resulted in a lower prevalence of smear-positive cases, irrespective of culture results observed in the survey conducted during 2001-2003 compared to that in the survey conducted during 1999-2001 (252 vs. 323 per 100,000; annual decline of 9%). Similarly, a decline in culture-positive cases, irrespective of smear results, was also observed (443 vs. 605; annual decline 11%).CONCLUSION:
The higher proportion of successful completion of treatment after DOTS implementation was associated with a substantial decline in the prevalence of TB. These findings showed that we are in the direction towards achieving the Millennium Development Goals (MDGs).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Tuberculosis
/
Female
/
Humans
/
Male
/
Clinical Protocols
/
Population Surveillance
/
Rural Health
/
Prevalence
/
Cohort Studies
/
Treatment Outcome
Type of study:
Etiology study
/
Practice guideline
/
Incidence study
/
Observational study
/
Prevalence study
/
Risk factors
/
Screening study
Country/Region as subject:
Asia
Language:
English
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS