Study of relapse and failure cases of CAT I retreated with CAT II under RNTCP--an eleven year follow up.
Article
in English
| IMSEAR
| ID: sea-110567
ABSTRACT
OBJECTIVE:
To analyse the treatment outcome of Cat I smear positive relapse and failure cases and their fate when treated with Cat II regimen under RNTCP.METHODS:
All Cat I smear positive relapse and failure TB patients treated with Category II regimen from 1994 to 2005 in a chest clinic of Delhi were analysed in this retrospective study. The re-treatment outcome data for relapse and failure cases of Cat I when treated with Cat II regimen was reviewed.RESULTS:
The study population included 5576 registered as Cat I sputum positive cases in Gulabi Bagh chest clinic from 1994 to 2005. A total of 190 (3.4%) failed on Cat I regimen. Further out of 4905 (87.9%) successfully treated Cat I patients, 442 (9%) presented as relapses. The treatment success rate for relapse and failure cases of Cat I when subsequently treated with Cat II regimen were 76.4% and 48.8% respectively, with a significantly higher failure rate (27.6%) among Cat I failures subsequently treated with Cat II regimen.CONCLUSION:
The failure cases of Cat I subsequently treated with Cat II were observed to have a significantly lower success rates (p < 0.05) as compared to relapse cases. The need for reappraisal of Cat II re-treatment regimen for failure cases among Cat I is suggested.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Time Factors
/
Tuberculosis
/
Remission Induction
/
Humans
/
Communicable Disease Control
/
Retrospective Studies
/
Follow-Up Studies
/
Treatment Failure
/
India
Type of study:
Observational study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Year:
2008
Type:
Article
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