Avirulent mutants of Macrophomina phaseolina and Aspergillus fumigatus initiate infection in Phaseolus mungo in the presence of phaseolinone; levamisole gives protection.
J Biosci
;
2000 Mar; 25(1): 73-80
Article
in English
| IMSEAR
| ID: sea-110694
ABSTRACT
To evaluate the role of phaseolinone, a phytotoxin produced by Macrophomina phaseolina, in disease initiation, three nontoxigenic avirulent mutants of the fungus were generated by UV-mutagenesis. Two of them were able to initiate infection in germinating Phaseolus mungo seeds only in the presence of phaseolinone. The minimum dose of phaseoli-none required for infection in 30% seedlings was 2 5 mg/ml. A human pathogen, Aspergillus fumigatus was also able to infect germinating seeds of P. mungo in the presence of 5 mg/ml concentration of phaseolinone. Phaseolinone seemed to facilitate infection by A. fumigatus, which is not normally phytopathogenic, by reducing the immunity of germinating seedlings in a nonspecific way. Levamisole, a non-specific immunopotentiator gave protection against infection induced by A. fumigatus at an optimum dose of 50 mg/ml. Sodium malonate prevented the effects of levamisole.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plant Diseases
/
Plants, Medicinal
/
Aspergillus fumigatus
/
Seeds
/
Adjuvants, Immunologic
/
Levamisole
/
Mitosporic Fungi
/
Drug Interactions
/
Immunity, Innate
/
Fabaceae
Language:
English
Journal:
J Biosci
Year:
2000
Type:
Article
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