Production of paclitaxel by Fusarium solani isolated from Taxus celebica.
J Biosci
;
2008 Jun; 33(2): 259-67
Article
in English
| IMSEAR
| ID: sea-110894
ABSTRACT
A fungus was isolated from the stem cuttings of Taxus celebica, which produced paclitaxel in liquid-grown cultures. The fungus was identified as Fusarium solani based on colony characteristics, morphology of conidia and the 26S rDNA sequence. Paclitaxel was identified by chromatographic and spectroscopic comparison with authentic paclitaxel and its cytotoxic activity towards Jurkat cells in vitro.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Molecular Sequence Data
/
Base Sequence
/
Chromatography, High Pressure Liquid
/
Paclitaxel
/
DNA, Plant
/
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
/
Jurkat Cells
/
Taxus
/
Fusarium
Type of study:
Prognostic study
Language:
English
Journal:
J Biosci
Year:
2008
Type:
Article
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