Dynamical complexity and temporal plasticity in pancreatic beta-cells.
J Biosci
;
2000 Jun; 25(2): 197-209
Article
in English
| IMSEAR
| ID: sea-110996
ABSTRACT
We discuss some of the biological and mathematical issues involved in understanding and modelling the bursting electrical activity in pancreatic beta-cells. These issues include single-cell versus islet behaviour, parameter heterogeneity, channel noise, the effects of hormones, neurotransmitters, and ions, and multiple slow biophysical processes. Some of the key experimental and modelling studies are described, and some of the major open questions are discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Biological Clocks
/
Humans
/
Acetylcholine
/
Cell Communication
/
Cell Separation
/
Calcium
/
Islets of Langerhans
/
Nonlinear Dynamics
/
Electrophysiology
/
Glucose
Type of study:
Prognostic study
Language:
English
Journal:
J Biosci
Year:
2000
Type:
Article
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