Molecular insights into the causes of male infertility.
J Biosci
;
2001 Nov; 26(4 Suppl): 429-35
Article
in English
| IMSEAR
| ID: sea-111073
ABSTRACT
Infertility is a reproductive health problem that affects many couples in the human population. About 13-18% of couple suffers from it and approximately one-half of all cases can be traced to either partner. Regardless of whether it is primary or secondary infertility, affected couples suffer from enormous emotional and psychological trauma and it can constitute a major life crisis in the social context. Many cases of idiopathic infertility have a genetic or molecular basis. The knowledge of the molecular genetics of male infertility is developing rapidly, new "spermatogenic genes" are being discovered and molecular diagnostic approaches (DNA chips) established. This will immensely help diagnostic and therapeutic approaches to alleviate human infertility. The present review provides an overview of the causes of human infertility, particularly the molecular basis of male infertility and its implications for clinical practice.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
X Chromosome
/
Y Chromosome
/
Female
/
Humans
/
Male
/
Gene Deletion
/
Reproductive Techniques, Assisted
/
Infertility, Female
/
Infertility, Male
Type of study:
Etiology study
Language:
English
Journal:
J Biosci
Year:
2001
Type:
Article
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