A model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential chemotactic sensitivity to cAMP and differential sensitivity to suppression of chemotaxis by ammonia.
J Biosci
;
2007 Mar; 32(2): 329-38
Article
in English
| IMSEAR
| ID: sea-111149
ABSTRACT
The three basic cell types in the migrating slug of Dictyostelium discoideum show differential chemotactic response to cyclic AMP (cAMP) and differential sensitivity to suppression of the chemotaxis by ammonia.The values of these parameters indicate a progressive maturation of chemotactic properties during the transdifferentiation of slug cell types.We present a model that explains the localization of the three cell types within the slug based on these chemotactic differences and on the maturation of their chemotactic properties.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Cell Differentiation
/
Chemotactic Factors
/
Chemotaxis
/
Cyclic AMP
/
Dictyostelium
/
Ammonia
/
Animals
/
Models, Biological
Type of study:
Prognostic study
Language:
English
Journal:
J Biosci
Year:
2007
Type:
Article
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