Application of electron spin resonance for evaluation of the level of free radicals in the myometrium in full-term pregnancy with normal labour and uterine inertia.
J Biosci
;
2003 Feb; 28(1): 19-21
Article
in English
| IMSEAR
| ID: sea-111284
ABSTRACT
In order to identify and quantify free radicals in the tissues of patients with normal physiological and pathological states of births, we developed a method to evaluate the amount of free radicals in myometrium of subplacental area and from body of uterus, using electron spin resonance spectroscopy. Analysis of the concentration of free radicals in the myometrium in full-term pregnancy with normal labour and during uterine inertia was studied. The activities of Ca2+-ATPase, cytochrome c oxidase and succinate dehydrogenase in samples of these tissues were tested too. Low free radical concentrations in these tissues were associated with disturbances in contractile activity of myometrium along with reduction of Ca2+-ATPase, cytochrome c oxidase and succinate dehydrogenase activity. There proved to be an association between the level of free radicals in the tissues and alteration in the physiological processes.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Succinate Dehydrogenase
/
Uterine Inertia
/
Female
/
Humans
/
Pregnancy
/
Calcium-Transporting ATPases
/
Electron Transport Complex IV
/
Electron Spin Resonance Spectroscopy
/
Delivery, Obstetric
/
Free Radicals
Language:
English
Journal:
J Biosci
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS