Colonic immunity in patients and amoebic liver abscess.
Article
in English
| IMSEAR
| ID: sea-111576
ABSTRACT
Secretory immunoglobulin A (S-IgA), coproantibody titre (antiamoebic) and IgA, IgG, IgM immunocytes in rectal mucosa were studied in 13 patients with amoebic liver abscess (ALA) prior to and 4-6 weeks after completion of antiamoebic therapy. Ten asymptomatic Entamoeba histolytica cyst passers and 17 healthy age and sex matched volunteers served as controls. Fecal S-IgA levels and counts of IgA bearing immunocytes in mucosa were significantly higher in patients with ALA and cyst passers as compared to healthy controls and showed a significant fall after treatment. Fecal antiamoebic antibodies were high in cyst passers and in cases of ALA after treatment. Raised levels of S-IgA and IgA class immunocyte counts probably indicate a local mucosal immune response directed at containing the infection.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rectum
/
Female
/
Humans
/
Male
/
Immunoglobulin A
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Immunoglobulin A, Secretory
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Immunoglobulin G
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Immunoglobulin M
/
Antibodies, Protozoan
/
Lymphocytes
Language:
English
Year:
1992
Type:
Article
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