Importance of mean parasite clearance time and recrudescence time and their role in gradation of Plasmodium falciparum resistance.

Pandya, A P; Barkakaty, B N; Narasimham, M V

Pandya, A P; Barkakaty, B N; Narasimham, M V.

Article in English | IMSEAR | ID: sea-111774

ABSTRACT

ABSTRACT

The present paper describes the relationship of Mean Parasite Clearance Time (MPCT) and Mean Parasite Recrudescence Time (MPRT) in the epidemiology of Plasmodium falciparum. The role of MPCT in grading the resistance of an area has been discussed. Further, MPRT revealed a positive correlationship with the percentage of RI resistant cases, and showed an increase with age. The ratio of MPRT/MPCT is an indicator of stability status of the resistance.

Subject(s)

Adolescent; Adult; Age Factors; Animals; Child; Child, Preschool; Chloroquine/pharmacology; Drug Evaluation; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum/blood; Male; Middle Aged; Plasmodium falciparum/drug effects; Recurrence; Remission Induction; Time Factors

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plasmodium falciparum / Recurrence / Time Factors / Remission Induction / Female / Humans / Male / Drug Resistance / Child / Child, Preschool Language: English Year: 1992 Type: Article

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