Detection of IgM antibodies in pulmonary tuberculosis by ELISA using A60 antigen.
Article
in English
| IMSEAR
| ID: sea-112648
ABSTRACT
An enzyme immunosorbent assay (ELISA) was evaluated as a serodiagnostic test in patients with active tuberculosis (Group I), clinically suspected pulmonary tuberculosis (Group II) and pulmonary diseases other than tuberculosis and normal healthy subjects (Group III). and compared with culture and sputum smear examination results. ELISA was found to have a sensitivity of 77.5% and a specificity of 87.5%. Sputum smear had a sensitivity of 65% and specificity of 100%. In patients clinically suspected to have pulmonary tuberculosis ELISA had a sensitivity of 60%. Thus ELISA using A60 antigen can facilitate the diagnosis of tuberculosis in patients with active as well as suspected pulmonary tuberculosis and can provide results within hours of receipt of samples.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sputum
/
Tuberculosis, Pulmonary
/
Female
/
Humans
/
Male
/
Immunoglobulin M
/
Enzyme-Linked Immunosorbent Assay
/
Case-Control Studies
/
Child
/
Sensitivity and Specificity
Type of study:
Diagnostic study
/
Observational study
Language:
English
Year:
1996
Type:
Article
Similar
MEDLINE
...
LILACS
LIS