Anti-inflammatory activities of methanol extracts from various seaweed species.
J Environ Biol
;
2008 Jul; 29(4): 465-9
Article
in English
| IMSEAR
| ID: sea-113478
ABSTRACT
Thirty-seven species of common seaweeds from the coast of Korea were screened for anti-inflammatory activity Methanol extracts of the seaweeds were tested against mouse ear edema and erythema induced by phorbol myristate acetate. At 40 mg ml(-1) of extract, edema was strongly suppressed by the seaweeds Undaria pinnatifida and Ulva linza, with relative inhibition of 85 and 84%, respectively These two seaweeds also showed the greatest suppression of erythema, with inhibition of 78 and 70%, respectively IC50 values of U. pinnatifida were 10, 15, and 18 mg ml(-1) when inflammation symptoms of edema, erythema, and blood flow, respectively were measured. The IC50 of U. linza was 20, 26, and 31 mg ml(-1) when edema, erythema, and blood flow, respectively, were measured. A linear correlation among inhibition rates of edema, erythema, and blood flow was observed with high confidence.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Seaweed
/
Blood Flow Velocity
/
Tetradecanoylphorbol Acetate
/
Plant Extracts
/
Inhibitory Concentration 50
/
Methanol
/
Dose-Response Relationship, Drug
/
Ear
/
Edema
/
Erythema
Country/Region as subject:
Asia
Language:
English
Journal:
J Environ Biol
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS