Effect of mercuric chloride on circulating hormones in adult albino rats.
J Environ Biol
;
2003 Oct; 24(4): 401-4
Article
in English
| IMSEAR
| ID: sea-113501
ABSTRACT
The effect of mercuric chloride at two different doses, 0.5 mg/kg body weight (low dose), 1 mg/kg body weight (high dose), for 30 days, was seen on the circulating hormones in the mature male albino rats. Testosterone level was markedly decreased in the low dose (P < 0.01) and high dose (P < 0.001) treated animals. The level of luteinizing hormone (LH) was also reduced in the low dose (P < 0.01) as well as in the high dose (P < 0.001) treated animals. However, follicle stimulating hormone (FSH) and prolactin (PRL) levels were found to be decreased only in the high dose (P < 0. 05) treated animals and no change was observed in the low dose treated animals. The changes in the hormone levels caused by the mercuric chloride treatment suggest the dysfunction of pituitary-testicular axis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pituitary Gland
/
Prolactin
/
Rats
/
Testis
/
Testosterone
/
Male
/
Luteinizing Hormone
/
Rats, Wistar
/
Follicle Stimulating Hormone
/
Animals
Language:
English
Journal:
J Environ Biol
Year:
2003
Type:
Article
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