In vivo studies on the effect of Ocimum sanctum L. leaf extract in modifying the genotoxicity induced by chromium and mercury in Allium root meristems.
J Environ Biol
;
2006 Jan; 27(1): 93-5
Article
in English
| IMSEAR
| ID: sea-113861
ABSTRACT
In vivo cytogenetic assay in Allium cepa root tip cells has been carried out to detect the modifying effect of Ocimum sanctum aqueous leaf extract against chromium (Cr) and mercury (Hg) induced genotoxicity. It was observed that the roots post-treated with the leaf extract showed highly significant (p < 0.001) recovery in mitotic index (MI) and chromosomal aberrations (CA) when compared to pre-treated (Cr/Hg) samples and the lower doses of the leaf extract were found to be more effective than higher doses. The present study reveals that the Ocimum sanctum leaf extract possesses the protective effect against Cr/Hg induced genetic damage.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Allium
/
Plant Extracts
/
Chromium
/
Chromosome Aberrations
/
Plant Roots
/
Plant Leaves
/
Meristem
/
Ocimum
/
Mercury
/
Mitotic Index
Language:
English
Journal:
J Environ Biol
Year:
2006
Type:
Article
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