Cloning, chromosome localization and features of a novel human gene, MATH2.
J Genet
;
2002 Apr; 81(1): 13-7
Article
in English
| IMSEAR
| ID: sea-114489
ABSTRACT
We report cloning and some features of a novel human gene, MATH2, which encodes a protein of 337 amino acid residues with a basic helix loop helix domain and exhibits 98% similarity to mouse Math2. Results of Northern blot analysis revealed two transcripts of the MATH2 gene of 1.7 kb and 2.4 kb in human brain. We localized MATH2 to chromosome 7 at 7p14-15 by matching with the Human Genome Sequence Database. Human MATH2 and mouse Math2 may have the same functions in the nervous system.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Transcription Factors
/
Chromosomes, Human, Pair 7
/
Humans
/
Molecular Sequence Data
/
Base Sequence
/
Chromosome Mapping
/
Amino Acid Sequence
/
Cloning, Molecular
/
Sequence Homology, Amino Acid
/
Helix-Loop-Helix Motifs
Language:
English
Journal:
J Genet
Year:
2002
Type:
Article
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