Leucocyte adhesion defect-1.
Indian Pediatr
;
2008 Jun; 45(6): 507-9
Article
in English
| IMSEAR
| ID: sea-11530
ABSTRACT
Leucocyte adhesion defect (LAD) is an inherited disorder of phagocytic function. It is characterized by inability of the leucocytes, in particular neutrophilis to migrate from the blood stream towards sites of inflammation. LAD -1 is characterized by the absence of b 2 integrins (CD 11 / CD18) on leucocytes. This disorder is characterized by delayed separation of the umbilical cord, recurrent severe infections, periodontitis, and delayed wound healing. We report an infant where the diagnosis was confirmed by flow cytometry.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Male
/
Leukocyte-Adhesion Deficiency Syndrome
/
Infant
Language:
English
Journal:
Indian Pediatr
Year:
2008
Type:
Article
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