Tinospora cordifolia induces colony stimulating activity in serum.
J Postgrad Med
;
1994 Oct-Dec; 40(4): 202-3
Article
in English
| IMSEAR
| ID: sea-115518
ABSTRACT
Tinospora cordifolia (Tc) is an Indian medicinal plant with proven immunomodulatory activity. This study was performed to elucidate its possible mechanism of action. We measured CFU-GM Cotony forming units of the granulocyte-macrophage series in serum of mice treated with Tc. We found that 10 days treatment with Tc (100 mg/ kg/d) induced a significant (p < 0.01) increase in the number of CFU-GM (255 +/- 49.32 vs 38.51 +/- 9.98) This suggests that activation of macrophages by Tc leads to increase in GM-CSF which leads to leucocytosis and improved neutrophil function.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plants, Medicinal
/
Female
/
Male
/
Adjuvants, Immunologic
/
Granulocyte-Macrophage Colony-Stimulating Factor
/
Animals
/
Macrophage Activation
/
Mice
/
Mice, Inbred Strains
Language:
English
Journal:
J Postgrad Med
Year:
1994
Type:
Article
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