Unusual haematological alterations in rheumatoid arthritis.
J Postgrad Med
;
2004 Jan-Mar; 50(1): 60-1
Article
in English
| IMSEAR
| ID: sea-116514
ABSTRACT
Three cases of rheumatoid arthritis (RA), presenting with refractory anaemia, thrombocytopenia and peripheral lymphocytosis respectively, were observed. In all the cases haematological manifestations were unrelated to disease activity or drug toxicity. These patients were detected to have pure red cell aplasia (PRCA) (normocytic normochromic anaemia, reticulocytopenia and absence of erythroid precursors in the bone marrow), immune thrombocytopenia (IT) (absence of splenomegaly and presence of increased megakaryocytes in the bone marrow) and multiple myeloma (MM) (lytic lesions on skull, paraproteinaemia and bone marrow plasmacytosis) respectively. PRCA and IT responded to glucocorticoids. Association with these three haematological alterations has rarely been reported. Our report highlights the need to regularly monitor blood counts in patients with RA.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Arthritis, Rheumatoid
/
Thrombocytopenia
/
Aged
/
Female
/
Humans
/
Male
/
Red-Cell Aplasia, Pure
/
Hematologic Diseases
/
Lymphocytosis
/
Middle Aged
Language:
English
Journal:
J Postgrad Med
Year:
2004
Type:
Article
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