Histiocytosis-X: role of histology and S-100 protein in grading the severity of disease.
J Postgrad Med
;
1990 Jan; 36(1): 16-9
Article
in English
| IMSEAR
| ID: sea-116682
ABSTRACT
Histiocytosis-X encompasses a wide clinical spectrum from a benign localised lesion to acute generalised disease with malignant behaviour. We have reviewed material from our 18 retrospective cases comparing histological features with clinical data. Degree of positivity for S-100 protein was studied by immunoperoxidase method. Our results indicate that diagnosis of histiocytosis-X necessitates histological confirmation but grading of histological criteria and S-100 positivity do not allow prediction of severity and extent of the disease.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Infant, Newborn
/
Immunohistochemistry
/
S100 Proteins
/
Child, Preschool
/
Histiocytosis, Langerhans-Cell
/
Infant
Type of study:
Prognostic study
Language:
English
Journal:
J Postgrad Med
Year:
1990
Type:
Article
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