Progressive systemic sclerosis (scleroderma), carcinoma breast and valvular heart disease: an unusual combination.
J Postgrad Med
;
2000 Jul-Sep; 46(3): 181-3
Article
in English
| IMSEAR
| ID: sea-116702
ABSTRACT
Systemic sclerosis is a multi system disorder characterised by fibrosis of skin and internal organs. There are reports of relation between cancer and polymyositis/dermatomyositis, but no overall association with systemic sclerosis. Reports of the coexistence of cancer and systemic sclerosis, however, emphasise a close temporal relation in their occurrence. Cardiac involvement in the form of myocardial fibrosis and pericarditis occurs frequently in systemic sclerosis, while valvular involvement has been reported only sporadically. We report a patient, admitted for adenocarcinoma of left breast who was found to have features of systemic sclerosis, pulmonary hypertension, gangrene of toes, and stenotic mitral valve disease. The possible mechanisms of the coincidence of the three disorders are discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Scleroderma, Systemic
/
Breast Neoplasms
/
Female
/
Humans
/
Follow-Up Studies
/
Carcinoma, Ductal, Breast
/
Risk Assessment
/
Middle Aged
/
Mitral Valve Insufficiency
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
J Postgrad Med
Year:
2000
Type:
Article
Similar
MEDLINE
...
LILACS
LIS