Malignant tumours of the minor salivary glands: a survival analysis of 17 years from a tertiary referral cancer centre.
J Postgrad Med
;
2003 Jan-Mar; 49(1): 25-8
Article
in English
| IMSEAR
| ID: sea-117033
ABSTRACT
BACKGROUND:
Malignant tumours of the minor salivary glands are rare and constitute less than 0.5% of all malignant neoplasms.AIM:
This study was carried out to evaluate the clinical presentation, site distribution, treatment, survival and predictors of survival in malignant minor salivary gland tumours.SETTING:
A tertiary care, superspeciality referral hospital.DESIGN:
Retrospective analysis. PATIENTS ANDMETHOD:
Forty-two cases of minor salivary gland tumours treated over a period of 17 years were reviewed for clinical presentation, histopathology, stage distribution, treatment and treatment outcome. STATISTICALANALYSIS:
Survival by Kaplan Meier Method and the outcomes were compared using log-rank test.RESULTS:
The mean age of the patients was 46.9 years with a male to female ratio of 1.41. Majority of the patients presented with a painless progressive swelling, with 13 (31%) of them in T2 stage. About one-third of the patients had palpable lymph nodes at presentation, while none had distant metastasis. Palate was the commonest site and mucoepidermoid carcinoma was the commonest hispathological type. About 1/3 of the patients were treated with primary surgery and were followed up by adjuvant radiotherapy. Seven patients underwent palliative treatment alone. Over a mean follow-up of 30 months, 5 patients failed. The disease free survival was 72% at 5-year, none of the factors studied were found to significantly influence survival.CONCLUSIONS:
Results of the present study suggest that minor salivary gland tumours should be treated with primary surgery irrespective of site and histological type to achieve best loco-regional control and survival.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Palate
/
Aged
/
Female
/
Humans
/
Male
/
Salivary Gland Neoplasms
/
Carcinoma
/
Survival Analysis
/
Retrospective Studies
/
Adolescent
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
J Postgrad Med
Year:
2003
Type:
Article
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