Biochemical changes in polymorphonuclear leucocytes in diabetic patients.
J Postgrad Med
;
1993 Oct-Dec; 39(4): 183-6
Article
in English
| IMSEAR
| ID: sea-117256
ABSTRACT
A study on the functional ability of polymorphonuclear leucocytes (PMNL) indicates that the total lysosomal enzyme levels viz. Beta-glucuronidase, lysozyme, acid phosphatase and alkaline phosphatase were not altered in diabetics, compared to that in control subjects. However, the findings also reveal that the release of these lysosomal enzymes in response to a particulate stimulus is impaired in diabetics. This suggests that the bactericidal capacity of these cells, which are involved in phagocytosis, is impaired in diabetics, making them more vulnerable to infections.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phagocyte Bactericidal Dysfunction
/
Recurrence
/
Female
/
Humans
/
Male
/
Case-Control Studies
/
Adult
/
Diabetes Complications
/
Infections
/
Lysosomes
Type of study:
Observational study
Language:
English
Journal:
J Postgrad Med
Year:
1993
Type:
Article
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