Suitability of laboratory animals for screening anti-hyperlipidemic agents.
J Postgrad Med
;
1989 Jul; 35(3): 162-70
Article
in English
| IMSEAR
| ID: sea-117348
ABSTRACT
The present study was undertaken to evaluate and compare the lipid profiles of various laboratory animals to that of human beings. The human subjects and animals included in the study were from three age groups based on key physiological states. A record of the usual dietary constituents and their daily consumption was maintained. The results indicated that the lipid profile of pigs and dogs bears similarity to that of human beings. Results also revealed that lipid profile was labile in the second group of these animals indicating that this age is suitable to bring about the required changes to produce a hyperlipidemic animal.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Poultry
/
Rabbits
/
Rats
/
Rats, Inbred Strains
/
Swine
/
Humans
/
Male
/
Dogs
/
Drug Evaluation, Preclinical
/
Guinea Pigs
Type of study:
Diagnostic study
/
Screening study
Language:
English
Journal:
J Postgrad Med
Year:
1989
Type:
Article
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