Thymoma: a pathological study of 50 cases.
J Postgrad Med
;
2004 Apr-Jun; 50(2): 94-7
Article
in English
| IMSEAR
| ID: sea-117624
ABSTRACT
BACKGROUND:
A combination of epithelial cells and lymphocytes results in a varied histomorphology of thymomas and consequent varied classification systems.AIM:
To correlate the Marino and Muller-Hermelink (MMH) classification with the invasive behaviour of thymomas. SETTING ANDDESIGN:
Retrospective analysis. MATERIALS ANDMETHOD:
Thymomas encountered in the past 21 years were re-classified with the MMH classification and correlated with Masaoka's staging and clinical presentation.RESULTS:
The thymomas formed 91% of the primary thymic epithelial tumours. Predominantly cortical thymomas (n=21) and cortical thymomas (n=22) were the common subtypes and 60% and 77% of these, respectively, were in stages II or III. Cystic change, necrosis or haemorrhage played no role in predicting invasive behaviour. Cortical epithelium correlated well with the presence of para-thymic syndromes, especially myasthenia gravis.CONCLUSION:
MMH classification is easy to apply. Cortical thymomas in stage I should be followed up for possible recurrence.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thymoma
/
Thymus Neoplasms
/
Female
/
Humans
/
Male
/
Child
/
Retrospective Studies
/
Adolescent
/
Adult
/
Middle Aged
Type of study:
Observational study
Language:
English
Journal:
J Postgrad Med
Year:
2004
Type:
Article
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