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Thymoma: a pathological study of 50 cases.
J Postgrad Med ; 2004 Apr-Jun; 50(2): 94-7
Article in English | IMSEAR | ID: sea-117624
ABSTRACT

BACKGROUND:

A combination of epithelial cells and lymphocytes results in a varied histomorphology of thymomas and consequent varied classification systems.

AIM:

To correlate the Marino and Muller-Hermelink (MMH) classification with the invasive behaviour of thymomas. SETTING AND

DESIGN:

Retrospective analysis. MATERIALS AND

METHOD:

Thymomas encountered in the past 21 years were re-classified with the MMH classification and correlated with Masaoka's staging and clinical presentation.

RESULTS:

The thymomas formed 91% of the primary thymic epithelial tumours. Predominantly cortical thymomas (n=21) and cortical thymomas (n=22) were the common subtypes and 60% and 77% of these, respectively, were in stages II or III. Cystic change, necrosis or haemorrhage played no role in predicting invasive behaviour. Cortical epithelium correlated well with the presence of para-thymic syndromes, especially myasthenia gravis.

CONCLUSION:

MMH classification is easy to apply. Cortical thymomas in stage I should be followed up for possible recurrence.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Thymoma / Thymus Neoplasms / Female / Humans / Male / Child / Retrospective Studies / Adolescent / Adult / Middle Aged Type of study: Observational study Language: English Journal: J Postgrad Med Year: 2004 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Thymoma / Thymus Neoplasms / Female / Humans / Male / Child / Retrospective Studies / Adolescent / Adult / Middle Aged Type of study: Observational study Language: English Journal: J Postgrad Med Year: 2004 Type: Article