Breast conservation therapy for breast cancer: patient profile and treatment outcome at a tertiary care cancer centre.
Article
in English
| IMSEAR
| ID: sea-118905
ABSTRACT
BACKGROUND:
Breast conservation therapy is a well-established treatment modality for early breast cancer. It is not widely practised in developing countries because of a lack of awareness and treatment facilities, and physician and patient bias. We analysed our experience of breast conservation therapy.METHODS:
We retrospectively reviewed 102 patients who had undergone breast conservation surgery and axillary dissection for breast cancer. Surgery was followed by 45 Gy of radiation to the whole breast and 15-20 Gy of tumour bed boost. All high risk patients received adjuvant systemic therapy. The disease profile, morbidity and treatment outcome were analysed.RESULTS:
Out of 902 patients, 102 underwent breast conservation therapy (90 had early breast cancer and 12 had locally advanced breast cancer). Only 19.6% of patients with early breast cancer received breast conservation therapy. One-third of the patients had had a prior surgical intervention. The mean tumour size was 2.8 cm, 44% had nodal involvement and 29% were oestrogen- and progesterone-receptor negative. At a mean follow up of 32 months, only 1 patient had local recurrence, and the 5-year projected disease-free and overall survival were 82% and 88%, respectively.CONCLUSION:
Breast conservation therapy should be offered to suitable breast cancer patients. Strict adherence to protocol-based therapy and active multidisciplinary coordination are crucial for a successful breast conservation therapy programme. Education of the patient as well as the physician population is necessary for increasing the breast conservation therapy rates in India.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Radiotherapy Dosage
/
Breast Neoplasms
/
Aged
/
Female
/
Humans
/
Mastectomy, Segmental
/
Retrospective Studies
/
Treatment Outcome
/
Adult
/
Middle Aged
Type of study:
Practice guideline
/
Observational study
Language:
English
Year:
2005
Type:
Article
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