Correction of serum electrolyte imbalance prevents cardiac arrhythmia during amphotericin B administration.
Article
in English
| IMSEAR
| ID: sea-119118
ABSTRACT
Arrhythmias and cardiac arrest have been reported during amphotericin B administration but no effective technique has been described to prevent them. I saw two patients with kala-azar resistant to sodium stibogluconate who developed cardiac arrest after amphotericin infusion (in spite of tolerating a test dose). Both had low levels of serum sodium, potassium and calcium. After these were corrected the amphotericin B was restarted and the course of treatment completed successfully. I suggest that prior to giving amphotericin B to patients with resistant kala-azar their electrolyte imbalance should be corrected.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Arrhythmias, Cardiac
/
Potassium
/
Sodium
/
Water-Electrolyte Imbalance
/
Female
/
Humans
/
Male
/
Child
/
Amphotericin B
/
Calcium
Language:
English
Year:
1995
Type:
Article
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