Clostridium difficile in antibiotic associated pediatric diarrhea.
Indian Pediatr
;
1994 Feb; 31(2): 121-6
Article
in English
| IMSEAR
| ID: sea-12005
ABSTRACT
A case control study was carried out at the medical wards of Dr. B.C. Roy Memorial Hospital for Children, Calcutta, between January and September 1989. One hundred eleven hospitalized children up to the age of 5 years, receiving antibiotics for different medical problems, developed antibiotic associated diarrhea. Isolation of Clostridium difficile as sole pathogen was very low (3.6%) from these patients. Fecal samples of 111 case matched control children were also screened for C.difficile. Only 2.7% fecal samples of control children were positive for C.difficile. All the strains of C.difficile isolated from antibiotic associated diarrhea cases showed neutralisable cytotoxin in in vitro test. In contrast none of the strains isolated from control children showed cytotoxicity. This study suggests that C.difficile is not an important pathogen related to antibiotic associated diarrhea in children at this hospital.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Infant, Newborn
/
Enterocolitis, Pseudomembranous
/
Case-Control Studies
/
Child, Preschool
/
Clostridioides difficile
/
Colitis
/
Developing Countries
/
Diarrhea, Infantile
/
Feces
Type of study:
Observational study
/
Risk factors
Language:
English
Journal:
Indian Pediatr
Year:
1994
Type:
Article
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