Desmoplastic infantile ganglioglioma -- a case report.
Neurol India
;
2004 Sep; 52(3): 384-6
Article
in English
| IMSEAR
| ID: sea-121694
ABSTRACT
Desmoplastic infantile ganglioglioma is a very rare supratentorial tumor occurring in the first two years of life. A five-month-old female infant presented with recurrent seizures, large head and loss of acquired milestones. Computerized Tomographic Scan of brain showed a large subarachnoid cyst with a solid intensely contrast enhancing tumor in the right temporoparietal region with severe degree of mass effect. Craniotomy and total excision of the tumor followed subsequently by subduro-peritoneal shunt for the extracerebral fluid collection was done. The child made good recovery. Histopathology revealed features of desmoplastic infantile ganglioglioma, viz., marked desmoplastic component with glial and neuronal elements. Immunohistochemistry showed positive staining for glial fibrillary acidic protein (GFAP) with areas of synaptophysin and chromogranin positivity. Desmoplastic infantile ganglioglioma is a rare tumor of infancy, which has excellent prognosis after total excision. No adjuvant therapy is required. This is the first Indian report of desmoplastic infantile ganglioglioma out of less than fifty cases reported worldwide.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Seizures
/
Brain Neoplasms
/
Female
/
Humans
/
Tomography, X-Ray Computed
/
Astrocytes
/
Ganglioglioma
/
Neurosurgical Procedures
/
Infant
Type of study:
Prognostic study
Language:
English
Journal:
Neurol India
Year:
2004
Type:
Article
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