Hairy cell leukaemia with advanced treatment - a case report.
Article
in English
| IMSEAR
| ID: sea-1224
ABSTRACT
A case of hairy cell leukaemia (HCL), a rare leukaemia, is reported here. The patient was presented with high grade continuous fever with left upper abdominal discomfort for 6 days. He was moderately anaemic, had no peripheral lymphadenopathy with mild hepatosplenomegaly. He was anaemic (Hb-7.8 gm/dl), total leukocyte count was 20 x 109/L. Peripheral blood film showed lymphocytosis (92%) with neutropenia (8%) and absolute neutophil count (ANC) was 1 x 109/L. On review, 88% of the peripheral cells had peripheral hairy projections resembling hairy cell (HC). Bone marrow examination was consistent with HCL (morrow hairy cell = 52%) including marker studies. Tartrate resistant acid phosphatase test (TRAP) was also positive. He had opportunistic mycobecterial infection giving a positive bronchial lavage for acid fast bacilli. After controlling the infection he was advised a single dose chemotherapy of 2-chlorodeoxyadenosine (2-CDA). After that he was in partial remission and after 25 months clinical and pathological relapses occurred and a second dose of 2-CDA was given and the patient went into complete remission.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Bone Marrow Examination
/
Remission Induction
/
Humans
/
Male
/
Leukemia, Hairy Cell
/
Treatment Outcome
/
Cladribine
/
Adult
/
Mycobacterium Infections
/
Antineoplastic Agents
Language:
English
Year:
2003
Type:
Article
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