Colorectal cancers--experience at a regional cancer centre in India.
Article
in English
| IMSEAR
| ID: sea-124297
ABSTRACT
BACKGROUND:
The incidence of colorectal cancer (CRC) shows a wide geographic variation and India along with other Asian and African countries has a low incidence. Most patients present with advanced disease and no uniform treatment guidelines are followed at present. PATIENTS ANDMETHODS:
An audit of 91 patients treated as per IRCH protocol between June 1994 and Jun 2000 in a single surgical unit was performed.RESULTS:
The mean age of patients was 45.3 years (18-90 years) and there was a predominance of rectal cancer patients (Rectal vs Colon = 76% vs 24%). Majority of the rectal cancers were low rectal cancers (67%) and abdominoperineal resection was the commonest surgical procedure performed(40). The inoperability rate was 24% and sphincter salvage rate was 13%. Seventy nine percent of patients had adenocarcinoma and 90% of CRC patients belonged to Astler-Collers stage B2 and C. A total of 37 patients also received adjuvant radiotherapy and only 39 out of 60 patients planned for adjuvant chemotherapy could complete the treatment. The operative mortality was 2.2% and morbidity was 18%. A total of 13 (14%) patients had relapse of disease (local 5, regional 3, distant 5).CONCLUSIONS:
A significant number of CRC patients in India present with advanced stage of disease and probably due to referral bias majority had low rectal cancers. By advocating multimodality protocols a good locoregional and systemic control can be achieved despite the advanced stage of presentation.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aged, 80 and over
/
Aged
/
Female
/
Humans
/
Male
/
Colorectal Neoplasms
/
Survival Analysis
/
Incidence
/
Retrospective Studies
/
Risk Factors
Type of study:
Etiology study
/
Practice guideline
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Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged80
Country/Region as subject:
Asia
Language:
English
Year:
2001
Type:
Article
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