Association of Helicobacter pylori with peptic perforation in Chattisgarh region of India.
Article
in English
| IMSEAR
| ID: sea-124564
ABSTRACT
BACKGROUND:
Helicobacter pylori is present in over 90% cases of peptic ulcer. There are very few reports regarding prevalence of H. pylori infection in peptic ulcer perforation which is the commonest complication of peptic ulcer disease. In the present study we have drawn this association. PATIENTS ANDMETHODS:
44 cases of peptic perforation were included in this study. Per-operative biopsy was taken from the margin of perforation. The criteria for H. pylori positivity were, Positive Rapid Urease Test and evidence of H. pylori infection on histological examination using Modified Giemsa and H&E stains.RESULTS:
Prevalence of H. pylori infection in peptic perforation was 61.4%. This is well above the usual prevalence in normal population of 45%. H. pylori infection was significantly more common in cases of chronic dyspepsia (> 6 months) and not significantly related to sex, blood group, addiction, family history of acid peptic disease and previous H2 blocker therapy. INFERENCE H. pylori is found more commonly in patients with peptic ulcer perforation than in those without.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Peptic Ulcer
/
Peptic Ulcer Perforation
/
Female
/
Humans
/
Male
/
Prevalence
/
Helicobacter pylori
/
Helicobacter Infections
/
Adult
/
India
Type of study:
Prevalence study
Country/Region as subject:
Asia
Language:
English
Year:
2000
Type:
Article
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