Thrombotic thrombocytopenic purpura.
Indian Pediatr
;
2004 Mar; 41(3): 277-9
Article
in English
| IMSEAR
| ID: sea-12489
ABSTRACT
A 6-year-old boy presented with microangiopathic hemolytic anemia, thrombo-cytopenia, altered sensorium and intractable bleeding. A diagnosis of thrombotic thrombocytopenic purpura was made and the child recovered dramatically after plasmapheresis. Recent developments in the understanding of TTP are reviewed, including the importance of a metaloprotease required to cleave multimers of von Willibrand factor.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Purpura, Thrombotic Thrombocytopenic
/
Autoantibodies
/
Humans
/
Male
/
Von Willebrand Factor
/
Metalloendopeptidases
/
Child
/
Plasmapheresis
/
Metalloproteases
/
ADAM Proteins
Language:
English
Journal:
Indian Pediatr
Year:
2004
Type:
Article
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