Hepatitis in falciparum malaria.
Article
in English
| IMSEAR
| ID: sea-124985
ABSTRACT
BACKGROUND:
Hepatocellular jaundice occurring in patients with falciparum malaria has been called as malarial hepatitis.METHODS:
We studied 95 consecutive patients admitted with falciparum malaria. Of these 20 had evidence of malarial hepatitis. Their clinical presentation, complications and response to treatment was compared with that of patients without evidence of malarial hepatitis.RESULTS:
The clinical presentation of these patients was not different from those without hepatitis. However, the incidence of complications such as renal failure (60% vs 25%; X2 = 8.47, p < 0.01), Adult Respiratory Distress Syndrome (35% vs 3%; X2 = 18.13, p < 0.001) and septicemia (20% vs 6%; X2 = 4.01, p < 0.05) was significantly higher. The mortality also was higher in the group of patients with malarial hepatitis (40% vs 17%; X2 = 4.85, p < 0.05).CONCLUSIONS:
We conclude that the presence of hepatitis in patients with falciparum malaria indicates a more severe illness with a higher incidence of complications and a poor prognosis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Aged
/
Female
/
Humans
/
Male
/
Chi-Square Distribution
/
Incidence
/
Adolescent
/
Malaria, Falciparum
/
Adult
Type of study:
Incidence study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Year:
1998
Type:
Article
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