Disseminated histoplasmosis

ABSTRACT

The clinical presentation of Disseminated Histoplasmosis is diverse and may simulate hepatic, blood, pulmonary and renal disease. Less commonly it may resemble meningitis endocarditis, adrenal insufficiency, gastro-intestinal disorders and cutaneous disease. Definite diagnosis rests on the demonstration of the fungal bodies in tissues and by isolation of fungus by culture. Two cases of disseminated histoplasmosis confirmed by such methods are reported. These two cases are probably first 2 cases of Histoplasma infection reported from Burma.